Gen AI https://www.neurealm.com/category/blogs/gen-ai/ Engineer. Modernize. Operate. With AI-First Approach Tue, 18 Feb 2025 04:45:18 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.3 https://www.neurealm.com/wp-content/uploads/2025/05/Favicon.svg Gen AI https://www.neurealm.com/category/blogs/gen-ai/ 32 32 Beyond LLMs: Unlocking Agentic AI with RAG https://www.neurealm.com/blogs/beyond-llms-unlocking-agentic-ai-with-rag/ Fri, 07 Feb 2025 12:37:31 +0000 https://20.204.20.159/gavsstaging.com/?p=18302 The post Beyond LLMs: Unlocking Agentic AI with RAG appeared first on Neurealm.

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The world of artificial intelligence (AI) has evolved at an unprecedented rate, particularly with the advent of Large Language Models (LLMs) like GPT-3, GPT-4, Transformers (Hugging Face), Bard, and BERT. These models are remarkable in their ability to generate human-like text, comprehend context, and perform a wide variety of language-based tasks. However, while LLMs possess impressive linguistic abilities, they also present several limitations:

  • Hallucinations: LLMs can sometimes generate factually incorrect or nonsensical information, often confidently.
  • Lack of real-time information: LLMs typically rely on pre-trained data, which may not reflect the latest information or real-time events.
  • Limited reasoning and common sense: While LLMs can process information, they often struggle with complex reasoning, common sense understanding, and real-world grounding.
  • Black box nature: The inner workings of many LLMs are complex and opaque, making it difficult to understand and explain their decision-making processes.
  • Ethical concerns: LLMs can perpetuate biases present in their training data and may generate harmful or misleading content.

These limitations hinder the broader application of LLMs in real-world scenarios that require real-time decision-making, interaction with dynamic environments, and adherence to factual accuracy. Enter Agentic AI, a new frontier in AI development, powered by Retrieval-Augmented Generation (RAG), which aims to overcome these limitations by enhancing the capabilities of LLMs.

In this blog, we will explore how Agentic AI with RAG is changing the landscape of AI in critical sectors like healthcare and communication, particularly in contact centers using chat and voice bots, and conversational AI. We’ll also discuss the synergy between LLMs, RAG, and Agentic AI and provide examples to demonstrate their transformative potential.

Overview: What Is Agentic AI with RAG?

Agentic AI with RAG combines the generative power of LLMs with real-time data retrieval, allowing AI systems to access up-to-date information from external sources. While LLMs excel at processing and generating text based on pre-existing knowledge, RAG-powered Agentic AI systems can retrieve information from knowledge bases, documents, and the internet to inform their responses. This combination enables Agentic AI to not only respond with more accurate and context-aware outputs but also to take autonomous actions based on the retrieved data.

The synergy between LLMs, RAG, and Agentic AI makes it possible to build intelligent systems that can perform complex tasks, interact dynamically with users, and make decisions based on real-world data.

Definition: What Is Agentic AI with RAG?

Agentic AI with RAG refers to AI systems that:

  1. Use LLMs for natural language understanding and generation
  2. Retrieve data from external sources (such as databases, APIs, or documents)
  3. Make decisions autonomously or provide recommendations based on the data retrieved

This technology creates an AI system that not only produces intelligent text outputs but also interacts with its environment and takes actions autonomously, opening new possibilities in industries like healthcare and customer support.

Capabilities of Agentic AI with RAG

  • Real-Time Information Retrieval: Agentic AI can query up-to-date knowledge sources in real time, allowing it to respond to rapidly changing data and ensure the accuracy and relevance of its responses.
  • Autonomous Decision-Making: These systems can take autonomous actions based on the information they retrieve. This may include initiating actions like sending an email, scheduling a task, or even making complex decisions such as recommending medical treatments or providing personalized customer support.
  • Contextual Awareness: By retrieving external data specific to the user’s situation, Agentic AI can generate responses that are highly relevant, precise, and adapted to real-world needs.
  • Multimodal Interaction: Agentic AI is capable of handling both text-based and voice-based interactions, making it versatile across different platforms (for example, chatbots, voice assistants, and conversational AI systems).

How it Works

The core of Agentic AI lies in the interplay between an LLM, an external data retrieval system, and a decision-making process. Here’s how it works:

  1. User Input: The user provides a query or request (for example, asking a medical assistant for treatment options or a customer asking about an order status).
  2. Data Retrieval: The system queries relevant, real-time data sources. In healthcare, this could involve pulling up the latest medical research or patient records; in customer support, it could be accessing real-time customer data or product information.
  3. Data Integration: The retrieved data is integrated into the LLM’s processing pipeline. The LLM then generates a response that is informed by both the model’s pre-existing knowledge and the newly retrieved data.
  4. Decision-Making and Action: Based on processed data, the AI can autonomously take action, such as providing recommendations, making a decision (for example, approving a refund), or escalating the issue to a human agent.

Key Characteristics of Agentic AI with RAG

  • Dynamic Data Interaction: Unlike traditional models, Agentic AI can access and use data from external sources, ensuring that its responses are always up-to-date.
  • Autonomous Action and Decision-Making: These systems do not just generate responses; they also make autonomous decisions based on real-time information, streamlining processes like customer service, healthcare diagnostics, and more.
  • Context-Driven Responses: By retrieving domain-specific information (for example, the latest medical guidelines or current product status), Agentic AI ensures responses are relevant and specific to the user’s situation.
  • Multi-Platform Support: Whether through text-based chatbots, voice assistants, or integrated conversational AI, Agentic AI can handle various forms of communication, making it adaptable to different use cases.

Limitations of Agentic AI with RAG

  • Data Dependency: The accuracy and effectiveness of Agentic AI are dependent on the quality, availability, and reliability of the external data sources it retrieves from. Incomplete or outdated data can lead to suboptimal outcomes.
  • Computational Load: Data retrieval and integration can be computationally expensive, potentially affecting performance, especially for complex or large-scale applications.
  • Privacy and Security Concerns: In sensitive domains like healthcare or customer service, Agentic AI needs to handle personal data securely and comply with privacy regulations (for example, HIPAA, GDPR).
  • Bias in External Data: If the external data used for decision-making is biased, the AI system could reflect and propagate those biases, which is a particular concern in healthcare and customer support.

Domain-Specific Examples

Healthcare Example

In healthcare, Agentic AI with RAG can transform patient care by providing real-time, data-driven insights. Imagine a virtual assistant that helps doctors diagnose and recommend treatments for patients.

  1. Retrieval: The assistant retrieves the latest clinical research and patient-specific data, such as symptoms, medical history, and lab results.
  2. Processing: The system integrates this information and consults its training on medical knowledge to generate a recommendation.
  3. Action: Based on the recommendations, the assistant could autonomously suggest a treatment plan or escalate the case to a human doctor if necessary.

For example, if a patient presents symptoms related to cardiovascular condition, the virtual assistant may pull recent research on heart disease and suggest specific tests or treatments.

Communication Example (Contact Center – Chat/Voice Bots)

In a contact center environment, Agentic AI with RAG can enhance customer service by improving response accuracy and decision-making in real-time.

  1. Retrieval: The chatbot or voice bot queries a database for the customer’s order details or the latest product information.
  2. Processing: The system generates a personalized, context-specific response based on the data retrieved.
  3. Action: If the customer’s order is delayed, the system could autonomously offer solutions, such as expedited shipping or a discount.

This helps improve customer satisfaction by providing timely, personalized responses and proactive solutions, minimizing the need for human intervention.

Synergy Between LLMs, RAG, and Agentic AI

Sr.No. Feature LLMs RAG Agentic AI
1 FeatureKnowledge Source LLMsStatic knowledge learned during training RAGDynamically retrieves up-to-date external data Agentic AIAccesses external data and autonomously makes decisions
2 FeatureData Processing LLMsProcesses input text based on patterns RAGRetrieves relevant information to enhance outputs Agentic AIIntegrates retrieved data and takes autonomous actions
3 FeatureContextual Relevance LLMsGenerates context-aware responses from its training data RAGEnhances LLM’s responses with real-time context Agentic AIMakes informed, context-specific decisions based on real-time data
4 FeaturePersonalization LLMsLimited personalization (based on training data) RAGPersonalizes by retrieving domain-specific data Agentic AITailors recommendations and actions based on user history and preferences
5 FeatureAutonomous Decision-Making LLMsNo decision-making, only text generation RAGProvides enriched output, but no autonomous action Agentic AICan autonomously perform tasks, for example, sending recommendations, processing requests
6 FeatureAdaptability LLMsStatic, limited by training data cut-off RAGAdapts to real-time information from external sources Agentic AIContinuously adapts based on evolving data and user interactions

Conclusion

Agentic AI with RAG marks a significant leap forward in the evolution of AI systems. By combining the natural language generation capabilities of LLMs with real-time data retrieval and autonomous decision-making, it is possible to create AI that can provide real-time, personalized, and contextually relevant solutions. In sectors like healthcare and customer service, this technology has the potential to streamline operations, improve customer experience, and enhance decision-making.

However, challenges such as data dependency, computational complexity, and privacy concerns must be addressed to fully realize the potential of Agentic AI. As these technologies continue to evolve, we can expect even greater improvements in AI systems that not only understand and generate text but also act on data and make informed decisions autonomously.

Author

Swapnil Warkar | Senior Principal Architect, Neurealm

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A Deep Dive into the Value Chain of Generative AI https://www.neurealm.com/blogs/a-deep-dive-into-the-value-chain-of-generative-ai/ Mon, 06 Nov 2023 09:43:56 +0000 https://20.204.40.202/?p=7059 The post A Deep Dive into the Value Chain of Generative AI appeared first on Neurealm.

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Since late 2022, generative AI technology surged, impressing business leaders and investors with its ability to create human-like text and images. OpenAI’s ChatGPT gained an astonishing one million users in just five days, outpacing Apple’s iPhone adoption. Facebook and Netflix took months and years, respectively, to reach the same user base. Domains like finance and language preservation are embracing generative AI’s novel capabilities, enabled by neural networks trained on vast data and using attention mechanisms to understand context and generate original content.

As generative AI systems are being created and utilized, a fresh value chain is arising to facilitate the training and utilization of this potent technology. At first glance, it might appear quite akin to the conventional AI value chain. In essence, out of the six main categories—computer hardware, cloud platforms, foundation models, model hubs and machine learning operations (MLOps), applications, and services—only the inclusion of foundation models is novel.

Author

Pramod M

Pramod has an overall experience of around 17 years in Aerospace, IT, Education & Product development. He holds a MBA degree from Leeds University Business School, UK and currently working with solutions & strategy team at Neurealm.

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Exciting Possibilities with Generative AI https://www.neurealm.com/blogs/exciting-possibilities-with-generative-ai/ Fri, 29 Sep 2023 17:39:40 +0000 https://20.204.40.202/?p=8027 The post Exciting Possibilities with Generative AI appeared first on Neurealm.

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Generative AI (GenAI) has great potential to streamline and automate many mundane and repetitive tasks that clutter our daily lives. It can assist in summarizing extensive meeting notes, condensing lengthy documents that one might need more time to read thoroughly, and even aiding in creating routine business documents. Generative AI is particularly adept at handling language, reasoning, and amalgamating different components of a task, which makes it a compelling solution for a wide array of use cases that were previously challenging to address.

The remarkable versatility of generative AI is undeniably one of its most thrilling aspects. These models can proficiently generate code, craft documents, compose music, and even produce video content, although the latter is still a work in progress.

Neurealm has been conducted an ‘Everything Products’ series of webinars and fireside chats. A recent session from the series was a ‘Fireside Chat on Generative AI with AWS’. The session had three speakers – Mr. Guiseppe Zappia, GenAI Expert and Senior Solutions Architect, AWS; Mr. Randy DeFauw, GenAI Expert and Senior Principal Solutions Architect, AWS; and Mr. Sameer Mahajan, Principal Architect at Neurealm. Mr. Mandar Gadre, a Technology Evangelist from Neurealm, moderated the session.

Scope of Generative AI

An interesting use case of GenAI is in Regulatory Compliance of email correspondence. The ability to finetune a model to adhere to specific SEC compliance guidelines was demonstrated. This enabled the model to scrutinize email content, flagging elements as compliant or non-compliant with the specified regulations. Furthermore, it provided recommendations for rewriting sections to ensure compliance. Such a solution would streamline review processes and mitigate risk for businesses. The company could have been penalized had the original versions of the emails been sent. This showcases the multifaceted value that generative AI can bring, reducing manual effort while safeguarding against potential liabilities.

Development of Products with Generative AI

Before focusing on generative AI for developing applications, it is essential to understand the usage funnel. At the top level, many model consumers build applications or services using existing models. Going further down the funnel, users need more model tuners to finetune existing models according to their domain requirements. The bottom of the funnel has very few model producers who build entirely new models from scratch.

Things to Consider before Development

In developing a general application, and even in machine learning projects, the initial step involves evaluating whether the problem at hand is a suitable candidate for machine learning. The next step is a vetting process to determine if the issue can be addressed using traditional programming techniques. It is essential to weigh the cost and complexity of machine learning solutions against more straightforward programming solutions. Often, it’s more cost-effective to build a specific program for a task rather than investing in creating, training, and deploying machine learning models.

If it is established that machine learning is the way to go, the next step is to do a cost-benefit analysis – the potential business benefits and an estimation of the return on investment, including the Total Cost of Ownership (TCO). This phase also involves decisions about real-time versus batch processing and model selection. Questions like model size, the need for training or finetuning, and techniques like retrieval augmented generation are explored to understand the project’s potential costs and expected outcomes.

These steps eliminate many ideas that might not bring the desired value or could be addressed through alternative means. What remains are the ideas that truly shine and are strong candidates for utilizing generative AI or machine learning.

Best Practices While Using Generative AI

When choosing the generative AI path, it is essential to avoid tightly coupling your application to a specific model. Instead, build abstraction layers between your application and the underlying model. The reason for this is the rapid evolution of these models. Keeping your application flexible and decoupled allows quicker adaptations and changes, potentially giving you a competitive edge. While others struggle with complete application refactors when switching underlying models, your agility in making these changes can become a strategic advantage.

Focusing on ROI and evaluating the real benefits is crucial before diving into generative AI projects. It’s about making a well-informed choice and not spreading resources thin.

Choosing the correct training data, capturing the context accurately, and ensuring data quality are equally significant factors.

In practice, finding the most miniature model that yields acceptable results often proves beneficial and then additional techniques to enhance its performance can be applied. Users can focus on finetuning, where a small model, with the proper adjustments, can outperform a significant model in specific scenarios. Additionally, leveraging techniques like retrieval augmented generation on a smaller model can provide better outcomes than using a large model without these enhancements.

The critical takeaway is starting with simpler, smaller models and expanding as needed. Rather than beginning with the largest model and paring it down, growing your model size is more effective based on practical reasons and requirements, ensuring a more efficient and cost-effective approach.

In terms of these trade-offs, model size is just one aspect, and there’s also the matter of the training data size. These choices involve striking a balance between the level of intelligence desired in the model and the available computational resources. It’s a complex interplay, and generative AI certainly adds another layer of complexity to these decisions.

While this blog is a gist of the insightful discussion, you can watch it entirely here. To watch our other webinars, please visit https://www.Neurealmtech.com/videos/ and https://www.gslab.com/webinars/.

Neurealm offers Generative AI Services by taking a methodical approach to tackle a wide range of challenges and explore exciting possibilities through the power of GenAI. We offer customized solutions tailored to your unique needs, delivering significant advantages to your business, customers, and employees. Simply stated, we make GenAI work for you responsibly and securely.

  • Conducting Goal Alignment workshops for people managers, encouraging them to view this process not merely as a measuring tool but as an avenue to cultivate responsibility and autonomy while focusing on both individual and collective growth.
  • Providing coaching and training to people managers across the organization, emphasizing Effective Performance Feedback conversations and empathetic listening.
  • Implementing Quarterly Performance Feedback as a significant game-changer, crucial for maintaining a continuous feedback mechanism.
  • Collaborating with a Consulting firm to ensure equitable compensation at work, benchmarked against industry standards and promoting fairness and parity.
  • Implementing a tailored Career Development Plan (CDP) based on the 3Es (Education, Exposure, Experience) to address the growth of all individuals.
  • Establishing ‘Galvanizers,’ a Top Talent Program designed for high-potential individuals and emerging leaders.

At Neurealm, it is also one of our stated goals to emerge as a better workplace for women. Our commitment to diversity and inclusion plays an integral role in our success. Even for some of the most business-critical roles, we have enabled our women colleagues to play their roles from remote locations, thus supporting their personal commitments and ensuring their professional growth. Additionally, we offer enhanced flexibility to women both before and after maternity leave.

We are thus driven to create an organization with a purpose, contribute to addressing some larger societal issues, by being a significant player in the healthcare tech space coupled with our innovative solutions and value to customers.

At Neurealm, we are dedicated to nurturing a culture that values every individual, their aspirations, and their journey within our family. The foundation of respect, integrity, trust, and empathy, embodied in our RITE pillars, sets the stage for a workplace that is aligned and purposefully driven.

Our colleagues have given us the vote of trust through the Great Place of Work recognition and are committed to sustaining a high trust and high performance culture. As we move forward in this journey, we remain steadfast in our pursuit of creating an environment that not only fosters success but also enriches lives. We look forward to continuously evolving, leveraging innovation, and making a lasting impact on our team, customers and the world we serve. Together, we aspire for excellence, united by a collective #SenseOfPurpose.

Author

Sangeeta Malkhede, Global Head of HR, Neurealm

Sangeeta Malkhede heads our Global HR team. A senior HR leader with strong convictions, values, and experiences, she has an innovative approach towards HR practice and at her previous leadership roles she drove overall HR to enable Culture of Performance, Building Leadership Talent, Organization Effectiveness, Change Management and Employee Engagement etc.

Sangeeta is an avid reader and a keen observer of human behavior. She enjoys playing & following Badminton, Tennis and Cricket, has a passion for cooking, travelling and hydroponic farming.

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Exploring the Potential of Generative AI https://www.neurealm.com/blogs/exploring-the-potential-of-generative-ai/ Wed, 23 Aug 2023 10:17:55 +0000 https://20.204.40.202/?p=8209 The post Exploring the Potential of Generative AI appeared first on Neurealm.

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Use Cases in Healthcare, BFSI, and IT Services

Unleashing the power of artificial intelligence, Generative AI has emerged as a ground-breaking technology that pushes the boundaries of automation further than ever before. By training on vast datasets, Generative AI models possess the remarkable ability to create diverse content, including text, visuals, audio, and even code, in response to natural language prompts, as depicted in the diagram below. In this blog, we delve into the exciting world of Generative AI, exploring its potential use cases across various industries, such as healthcare, banking, financial services, and insurance (BFSI), and IT services.

Generative AI Use cases

Unleashing the power of artificial intelligence, Generative AI has emerged as a ground-breaking technology that pushes the boundaries of automation further than ever before. By training on vast datasets, Generative AI models possess the remarkable ability to create diverse content, including text, visuals, audio, and even code, in response to natural language prompts, as depicted in the diagram below. In this blog, we delve into the exciting world of Generative AI, exploring its potential use cases across various industries, such as healthcare, banking, financial services, and insurance (BFSI), and IT services.

Healthcare

Generative Artificial Intelligence holds immense potential as a digital assistant for physicians and healthcare providers, revolutionizing the accuracy of patient diagnoses. By analyzing a comprehensive range of data from past health records, including medical notes, medical images, prescription, wearable devices data, lifestyle information etc., it can offer them a personalized treatment plan/wellness plan, recommendation on whether to increase or decrease cost of insurance, value of insurance coverage and so on. The application of Generative AI in healthcare has the potential to significantly enhance patient care and outcomes.

Banking, Financial Services and Insurance (BFSI)

Generative AI offers numerous possibilities for the BFSI industry across the globe in achieving operational excellence. By harnessing its capabilities, the BFSI industry can optimize processes such as fraud detection, risk management, and real-time decision making. Generative AI also facilitates tasks such as writing assistance, data analysis, report summarization, and speech-to-text conversion, streamlining documentation processes. Moreover, virtual assistants powered by Generative AI, such as chatbots, prove instrumental in efficiently handling customer complaints and queries, allowing for more personalized and tailored services that enhance customer satisfaction. By empowering employees with advanced capabilities and driving productivity, Generative AI adds substantial business value to the BFSI industry.

IT – Software development & Infrastructure Services

Generative AI can be leveraged to read the logs of events, errors, warnings, and sessions of various devices (router, network switches, firewall, wireless devices, servers etc.,) and recommend early warnings, preventive maintenance plan, customized best practices and recommendation plan on which processes needs attention.

Knowledge Transition between vendor and customer is a challenge. In many cases, documented information about the IT Landscape / Infrastructure, Software application(s), Architecture, Design, known errors / issues/known risk(s), Knowledge Base Articles, SOP – Standard Operating Procedure etc., for Key / critical business system may not be available. By leveraging Generative AI, IT staff members who possess knowledge about the systems and applications can effectively document this knowledge, mitigating the business risks associated with reliance on key individuals or contractors who hold such information. Furthermore, this approach helps new team members get the right information, learn the right processes, and decreases the Mean Time to Repair, resulting in improved productivity through the consistent capture and maintenance of this knowledge.

In Agile projects, grooming plays a pivotal role in ensuring that user stories are thoroughly discussed, enabling the team to gain a comprehensive understanding of the required functionality. This includes considerations for design, integrations, and expected user interactions. Generative AI can be instrumental in documenting these discussions, capturing, and maintaining such knowledge. As a result, productivity is enhanced, and there is reduced dependence on key team members, leading to more efficient project execution.

The advent of Generative AI has opened up a world of possibilities across various industries, revolutionizing the way we approach automation and content creation. From healthcare to banking, financial services, and even IT services, Generative AI has showcased its potential to enhance operations, improve outcomes, and drive productivity. By leveraging its capabilities, healthcare providers can achieve more accurate diagnoses and personalized treatment plans, while the BFSI industry can optimize processes, detect fraud, and deliver tailored services to customers. In the realm of IT, Generative AI can streamline documentation, facilitate knowledge transfer, and improve productivity by capturing and maintaining intellectual knowledge.

With each use case, Generative AI demonstrates its power to transform industries, advance innovation, and unlock new frontiers of possibility. However, there must be a governance/review mechanism should be put in place to review the outcome of Generative AI to ensure the technology is rightly utilized without compromising privacy and compliances.

 

Author

Sekar T

Sekar has around 30+ years of experience in IT Services/Product Management. Over his careeer, he has managed Product Engineering/Development, Software Application Services, IT Infrastructure services,Digital Transformation, GRC, BCP, Automation, Continual Improvement. He has also designed, implemented and managed Certification programs like SEI-CMI-DEV & SVC, ISO 9001, ISO 27001, ISO 45001, ISO 22301, HIPAA, SOC2, GDPR, PCI-DSS, NIST etc.

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Will AI and Generative AI driven Digital Therapeutics be the keystone in the grand arch for Pharma, as it gears up for more drugs getting off-patent and off-exclusivity? https://www.neurealm.com/blogs/will-ai-and-generative-ai-driven-digital-therapeutics-be-the-keystone-in-the-grand-arch-for-pharma-as-it-gears-up-for-more-drugs-getting-off-patent-and-off-exclusivity/ Wed, 19 Jul 2023 04:57:37 +0000 https://20.204.40.202/?p=9019 The post Will AI and Generative AI driven Digital Therapeutics be the keystone in the grand arch for Pharma, as it gears up for more drugs getting off-patent and off-exclusivity? appeared first on Neurealm.

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“It is the best of times, it is the worst of times; everything is automated, everything is complicated; it is the age of human limitlessness, it is the age of artificial intelligence; it is the epoch of real-time data, it is the epoch of generated data” – adapting Dickens to the fictitious reality of our times!

The increasing adoption of digital therapeutics by the pharmaceutical industry is leading to significant innovations that are enhancing patient outcomes. However, investments in this space are a result of the fortitude of a few forward-thinking innovators and early adopters. It is a huge conceptual challenge to align digital therapeutics to prescription therapeutics since such initiatives require a comprehensive and multi-faceted approach involving credibility building, value demonstration, and stakeholder education.

Between now and the end of this decade, two events in tandem will push the spend on digital therapeutics from discretionary to essential.

The first revolves around several blockbuster drugs losing their protective patents and exclusivity during this period. This shift will compel pharmaceutical companies to prioritize product differentiation for competitive advantage and look beyond drug efficacy and effectiveness. Consequently, the industry will increasingly embrace a digital and patient-centric approach, focusing on patient engagement and empowerment, personalized care plans, tailored interventions, evidence-based practices, and real-time data for insights and treatment support. Collaborations with healthcare providers and strategic plans for reach and access to care institutions, healthcare professionals, and patients will be prevalent.

The second is the rapid evolution of Artificial Intelligence (AI) and Machine Learning (ML) technologies, now unavoidable, with far-reaching disruptive potential across industries and business functions. In the context of digital therapeutics, AI and ML bring about game-changing advancements. Digital therapeutics, viewed as digital applications that complement and differentiate treatment pathways and drug offerings, will serve as catalysts for patient engagement and physician enablement. AI and ML-driven digital therapeutics will have the capability to not only track but also predict clinical outcomes, proactively make evidence-based interventions, and extend remote patient monitoring beyond conventional parameters.

Digital Therapeutics (DTx) to AI Driven Digital Therapeutics (DTx.AI)

Standard DTx architectures focused on capturing and analyzing real-world patient data to support personalized care through mobile and web platforms. They enabled real-time data collection from wearables, devices, sensors, and medical equipment while facilitating connectivity with Electronic Medical Records (EMRs). They also offered data analytics, insights, treatment evaluation, monitoring tools, and extended support for cognitive behavioral therapy, gamification, lifestyle management, and wellness awareness.

DTx.AI incorporates therapeutic algorithms and machine learning models for personalized algorithmic decision making based on evidence-based validation. Machine learning techniques enable faster and more precise learning from data sets, identification of patterns, and correlations that recommend personalized treatment plans based on individual patient characteristics. AI algorithms can analyze various patient data, including medical history, genetic information, and lifestyle factors. By continuously monitoring and adjusting treatment plans, AI-powered digital therapeutics optimize treatment efficacy while minimizing adverse effects.

Initiatives leveraging AI in digital therapeutics help detect potential adverse events and drug interactions and contribute to ongoing pharmacovigilance and drug safety monitoring. AI enhances the reliability of remote patient monitoring and disease management by swiftly and accurately identifying patterns, deviations, and anomalies. Through the integration of appropriate alert systems, AI ensures timely notifications and alerts.

Furthermore, AI transforms DTx from being lifestyle and behavioral assistance tools to becoming active unassisted behavior modification and cognitive therapy support systems for patients. It enables information-driven and interactive engagements, offering comprehensive and personalized experiences.

Digital Therapeutics and Generative AI (DTx.GenAI)

The adoption of DTx.AI is paving the way for readiness and integration with generative AI. Although ethical, regulatory, reliability, and bias concerns require careful navigation, generative AI introduces the next level of possibilities.

Generative AI in Digital Therapeutic solutions (DTx.GenAI) enhances and refines machine learning models through feature extraction capabilities. By incorporating Natural Language Processing (NLP) and image processing, DTx.GenAI identifies and extracts only the necessary data sets and patterns for functioning of the models. This continuous learning, fine tuning, selection, and extraction process helps imbibe new data quickly to bring in dynamic improvements in therapeutic interventions.

DTx.GenAI will leverage generative models for selection and training, utilizing deep learning, reinforcement learning, and autoencoders for model selection. These capabilities facilitate the creation of new content resembling real-world data/ content from the machine learning model, and existing data. The training capability helps create newer data/ content resembling real world data/ content. A constant quest between creating close-to-real data and distinguishing real from created data helps refine the model. This generative AI capability enables simulations and training for patients and healthcare providers, optimizing treatment plans and post-treatment care. For pharmaceutical companies, this capability helps arrive at insights and predictive analytics, extrapolating beyond the available real population and data.

With DT.GenAI focusing on generating data rather than simply making decisions or predictions, the future of digital therapeutic solutions will heavily depend on user interactions and inputs. Feedback mechanisms and surveys will play a vital role in analyzing effectiveness and fine-tuning the models.

 

The ultimate payback is the possibility to extend beyond the treatment under focus. Comprehensive analysis encompassing commercial launches, real-world data, past trials data, genomic and proteomic information, uncovers more precise correlations, provides insights for target identification and refinement of molecules in drug discovery, and influences trial protocol designs for new treatment options or other therapeutic areas.

A Customer Success Story

This case study highlights our digital therapeutics intervention for a customer who has transformed biochemical investigations for oncology patients, enabling them to perform these tests from the comfort of their own homes.

Overview

Patients undergoing chemotherapy require regular urine tests, which traditionally involves visiting an out-patient facility or lab for analysis. Our customer’s goal was to minimize delays and enhance convenience for these patients by enabling them to complete the entire test remotely.

The Solution

The team of expert data scientists and AI/ML engineers from Neurealm enabled the customer to successfully revolutionize remote patient monitoring for oncology patients post chemotherapy through an ML enabled remote urine analysis system. The solution delivers convenience, speed, and efficiency to traditional laboratory tests.

To turn the customer’s vision into reality, Neurealm had to overcome several challenges. It was important to create an intuitive and seamless user experience to cater to non-tech-savvy users and patients who are quite often under a lot of emotional stress after chemotherapy. The solution had to be compatible with a wide variety of mobile devices and laptops for better accessibility. Concerns relating to data access controls, confidentiality, secure data transmission and storage had to be adequately addressed. The accuracy of the ML model needed to match the level of credibility expected by medical experts. Extracting relevant features from urine test strip images required deep image processing knowledge, considering factors like noise and variability.

ML and Data Science Process

To develop this ML-based remote urine analysis solution, a systematic data science process was adopted that involved choosing the right ML model after experimentation, extensive sample data collection to train the model, development of applications to capture the test strip images, extraction of relevant features from the images, handling of noise and variability, real-time transmission of results, and user-friendly, diagnostic reporting. Anonymized data was stored and made available for further research. Effective data engineering ensured seamless flow of data throughout the system encased within strict regulatory compliance, data protection, and documentation.

Machine learning and advanced technologies helped provide instant diagnostic reports, facilitated communication with doctors, and streamlined payment processes. Additionally, the data collected across the patient population was used for analytics while ensuring patient confidentiality.

You can find more details on the solution here
https://www.gslab.com/downloads/Remote-urine-analysis-for-cancer-patients-at-home-using-machine-learning.pdf

To find out how the solution can be customized for your specific needs, please reach out to marketing@gslab.com

Author

Dr. Vinod Sanjay

Dr. Vinod Sanjay leads the Life Sciences practice at Neurealm. His focus is on shaping digital ecosystems and next-generation business models for Life Sciences. As a consulting and technology partner, he has led several high-impact consulting engagements and technology transformation projects.

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Transforming Healthcare Sector with Generative AI https://www.neurealm.com/blogs/transforming-healthcare-sector-with-generative-ai/ Mon, 27 Mar 2023 05:42:43 +0000 https://20.204.40.202/?p=11712 The post Transforming Healthcare Sector with Generative AI appeared first on Neurealm.

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The health industry has undergone various digital disruptions throughout the years. Healthcare organizations closely monitor emerging digital technologies that may alter the industry. Healthcare organizations were quick to react when AI first entered the scene. They applied AI to many different tasks, including better patient care, report generation, research, and many others. Over the years, new AI-led technologies evolved inside the healthcare sector. AIOps in healthcare and generative AI are the hottest topics in terms of cutting-edge medical technology. For better diagnosis and treatment strategies, generative AI is already widely used in the healthcare industry worldwide. Read on to explore how generative AI and AIOps are revolutionizing the healthcare business.

Understanding the concept of Generative AI

A subset of artificial intelligence called “generative AI” aims to create new content. The input data is used to generate the new content. The input data could be unstructured or normal text. The input is transformed into various sorts of content using generative AI, depending on the needs. Images, text, audio, and other kinds of artificial data can be created by generative AI. Generative AI could only produce text data when it first appeared in the 1960s. The first generative AI-based content was created by chatbots.

Over the years, advancements in generative AI opened new doors. Generative adversarial networks came into the scene that could produce graphics, videos, and images. The best part of generative AI is that it can produce new content within seconds. Healthcare entities use generative AI to create medical imagery, MRI reports, and X-rays quickly. Since timing is critical in the healthcare sector, generative AI helps increase the speed of generating new content. Many healthcare entities also use generative AI to create custom treatment plans for different patients based on their treatment history. There are other use cases of generative AI in the healthcare sector, from improved drug discovery to health management.

Understanding how does generative AI help in the healthcare sector

Healthcare sector experiences benefits from every new-age technology. Healthcare entities may not invest in new-age technologies if they don’t see the gain from it. Let’s take AIOps in healthcare for example, it is used to increase service availability of software systems. The following are few of the benefits of using generative AI in the healthcare sector:

1. Modern and Advanced Drug development

Healthcare entities invest heavily in drug discovery and development. The discovery of a new drug for an existing medical condition can help healthcare entities boost their ROIs. Newly synthesised drugs must be tested on animals or humans before launching into the market. However, there is always a risk involved with drug testing on animals or humans. Generative AI can help identify the right candidates for drug testing based on their bodily functions. It can also run simulated tests on different candidates in synthetic environments. When the chances of success are high, a real test is performed on the selected candidates.

2. Personalised care plans

A custom treatment plan is prepared according to the medical history of a patient. The bodily functions of a patient are also considered for creating a custom medical plan. However, healthcare entities fail to create custom treatment plans for each patient. Since the healthcare sector deals with many patients daily, it is a challenge to create a personalised treatment plan for each patient. Generative AI can take the medical history, symptoms, and bodily functions of the patient as input to generate custom treatment plans. Healthcare entities do not have to worry about the service availability of a software system that generates treatment plans. Since generative AI can produce custom treatment plans within seconds, there is no need for an external software system.

3. Modern and advanced medical imagery

Traditional medical imaging solutions produce reports after a long period. At the same time, healthcare entities also must worry about the service availability of the medical imaging solution. If the software solution loses its service reliability, the healthcare entity might fail to produce medical images, x-rays, and MRI reports. With generative AI, the time taken to produce medical images is reduced drastically. Also, generative AI can identify abnormalities in medical images. Doctors and diagnostic experts will be informed of the existing problem by the generative AI system.

4. Better healthcare initiatives

Generative AI can analyse large amounts of data within seconds. Healthcare entities have to focus on population health management to launch specific services. For example, healthcare entities might deploy new treatment techniques for people in an area known to possess hereditary diseases. Generative AI can analyse demographic information on a granular level and generate rich insights. If healthcare entities are looking to launch healthcare schemes for some areas or unrecognised communities, generative AI is the right choice. Even government healthcare organisations can use generative AI for better population health management. Governments are expected to invest heavily in generative AI for launching effective public healthcare schemes.

The necessity for Generative AI regulation in the healthcare industry

There is a need to regulate generative AI in the healthcare industry. The healthcare sector is all about precision and accuracy. A second delay in service availability can cause a patient his/her life. For the same rationale, healthcare entities must use technologies that always make the right decisions. Many healthcare organisations are still researching the possibilities of generative AI. It is found that generative AI can be biased or opinionated at times.

When generative AI is biased, a healthcare organisation might face ethical concerns. Healthcare entities cannot depend on biased software solutions that might pose a risk to patients. However, the issue can be solved by training the generative AI model in the right way. Misuse of generative AI is another ethical concern for a healthcare entity. Employees might think that generative AI can replace their jobs. A healthcare entity must focus on navigating through the ethical concerns of generative AI.

Conclusion

The implementation must be done correctly, whether it is generative AI or AIOps in healthcare. You cannot expect generative AI systems that have not been trained to produce better judgements. An organisation must strive to address ethical issues in addition to training generative AI models.

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